Applied Research Projects and Consulting

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I am offering Consulting Services in Flow Cytometry and Cell-Based Assay Design.
Contact jpetriz for more information.

Research Projects (1991-2022). More than thirty years of experience in Flow Cytometry analysis of Cancer, Multidrug Resistance and Stem Cells.

Immune response. PD-1/PD-L1 checkpoint.

Nanocytometry. Flow virometry. Nanoplastics.

Platelet Function Analysis. Platelet Function Analysis.

Design of consensus protocols for safety, quality and standardization of CD34+ cells after-thawing.

Study of the mechanisms by which ABC transporters differentially activates low- or high-level transduction
cell signaling: Potential role to protect the stem cell compartment.

The use of anticancer drug libraries to study the reversal of multidrug resistance in Side Population cancer stem cells.

Sequential Immune Disruptions in Chronic Fatigue Syndrome.

Murine xenograft models for human ovary, testis, prostate, pancreas and colon cancers: Detection of bone marrow infiltration by Side Population cells.

Development of a new Cytomic Platform for stem cell systems biology.

FACS-based isolation of normal and cancer stem cells originated from the Side Population. Association with the gene expression in highly purified preparations of stem cell subsets.

Flow-FISH and CD34+/CD34- cell analysis as a measure of the presence and quality of Hematopoietic Stem Cells.

Quality Assessment of Autologous Haematopoietic Blood Progenitor and Stem Cell Grafting: A prospective registration study.

Identification and characterization of prostate cancer stem cells. Hormone-resistance and intermittent androgen supression.

Study of the contribution of vascular progenitor cells in vascular lesion and in repair mechanisms in pulmonary circulation in COPD.

New flow cytometric strategies for whole blood immunostaining.

Gene expression alterations, apoptosis and mitochondrial toxicity in adipocytes. Lipodistrophy ethiopathogenesis and its association with antiretroviral therapy.

Preparation and characterization of anti-CD34 immunoliposomes entrapping doxorubicin. Gene transfer.

Positive selection of CD34+ cells using immunoliposomes. Potential applications for autologous bone marrow transplantation.

Characterization and selection of normal and malignant progenitors in chronic myelogenous leukemia.

Study of regulatory factors affecting growth, cell proliferation and prognosis in hypophysary adenomas.

Genetic instability in colorectal cancers and its role in tumor progression. Molecular prognostic factors.

Detection and significance of minimal residual disease in acute myelogenous leukemia and non-Hodgkin lymphomas.

Prognostic value of DNA ploidy in women with node negative breast cancer.